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NCCT Surgical Technologist - Tech in Surgery (TS-C) Practice Tests & Test Prep by Exam Edge


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NCCT Surgical Technologist Sample Test

1 of 5

Which of the following is a mucosal protective drug?





Correct Answer:
sucralfate
sucralfate is a medication primarily used as a mucosal protectant in the gastrointestinal (gi) tract. it is specifically designed to treat and prevent ulcers in the stomach and upper part of the small intestine. unlike typical antacids or acid suppressors, sucralfate works by forming a protective barrier over the ulcerated areas. this barrier shields the underlying tissue from further injury caused by stomach acid and digestive enzymes, thus allowing the ulcer to heal more effectively.

the mechanism of action of sucralfate involves its reaction with hydrochloric acid in the stomach to form a viscous, paste-like substance. this substance adheres to the proteinaceous exudate found at ulcer sites, thus creating a physical barrier that protects the ulcer from further aggression by acid and pepsin (a digestive enzyme in the stomach). in addition to this barrier formation, sucralfate also stimulates prostaglandin production, which helps in protecting the stomach lining and promoting ulcer healing.

it's important to note that sucralfate does not significantly alter the acidity of the stomach or the production of gastric acid. instead, its primary function is protective. this makes sucralfate particularly valuable for patients who require ongoing treatment with medications that can irritate the gi tract, such as nsaids (like naproxen), or for those with a history of gi ulcers.

although sucralfate is effective in managing peptic ulcers, it is not typically used for general symptoms of indigestion or heartburn where antacids or acid suppressors are more appropriate. its therapeutic effect is most pronounced in the environment of existing ulcers or erosions where its adhesive and protective qualities can be maximally utilized.

in summary, sucralfate is a mucosal protective drug, distinct in its function and utility, primarily used to manage and heal gastric and duodenal ulcers by creating a protective barrier against acidic and enzymatic irritation. it is a critical component in the management of gi tract injuries, particularly in situations where the mucosal lining is compromised.


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