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Canadian Medical Laboratory Assistants - Blogs Sample Questions

Which of the following drugs is NOT a tricyclic antidepressant?

Correct Answer:
phenytoin


the question asks to identify which among the listed drugs is not a tricyclic antidepressant. the correct answer is phenytoin. this is because phenytoin does not belong to the class of tricyclic antidepressants but is instead classified as an anticonvulsant.

tricyclic antidepressants (tcas) are a class of medications primarily used to treat depression, anxiety disorders, and certain types of pain. they work by altering the levels of neurotransmitters in the brain, such as serotonin and norepinephrine, to help improve mood and pain perception. examples of tricyclic antidepressants include amitriptyline, imipramine, and doxepin, all of which were options in the list provided in the question except for phenytoin.

on the other hand, phenytoin is utilized primarily for its anticonvulsant properties. it is commonly prescribed to manage and prevent seizures in conditions like epilepsy. phenytoin operates by stabilizing the threshold against excitability in the brain, which helps to prevent seizure activity. additionally, it can be used in the treatment of neuropathic pain and as a prophylactic in brain surgery to mitigate the risk of post-traumatic seizures. however, it is not used for treating depressive disorders.

thus, among the medications listed—amitriptyline, imipramine, doxepin, and phenytoin—phenytoin is correctly identified as not being a tricyclic antidepressant. its primary use in treating seizure disorders distinguishes it from the other mentioned drugs, which are used to alleviate symptoms of depression.