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CPMHN - Canadian Psych/Mental Health Nursing (CPMHN) Practice Tests & Test Prep by Exam Edge - Related Blogs



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Canadian Psychiatric/Mental Health Nursing Examination - Blogs Sample Questions

What might decrease the absorption of lorazepam?

Correct Answer:
valproic acid


valproic acid, a medication primarily used to treat epilepsy and bipolar disorder, can interfere with the absorption of lorazepam, a benzodiazepine used for anxiety, insomnia, and seizure control. this interaction occurs because valproic acid can modify gastric and liver enzymes that are essential for the metabolism and absorption of various drugs, including lorazepam.

when valproic acid is administered, it may alter the level of enzymes in the liver, particularly those belonging to the cytochrome p450 system, which plays a significant role in drug metabolism. although valproic acid generally inhibits these enzymes, the specific interaction with lorazepam leads to decreased absorption rather than an alteration in metabolism. this means that when both drugs are taken together, the effectiveness of lorazepam could be reduced due to its lower absorption rate.

in contrast, the other substances listed such as barbiturates, antipsychotics, and alcohol do not decrease the absorption of lorazepam but rather tend to increase the central nervous system (cns) depressant effects of lorazepam. this increase in cns depressant effects can lead to enhanced sedation, decreased cognitive function, and other related symptoms, which could be dangerous in certain situations.

therefore, it is crucial to manage the co-administration of lorazepam with valproic acid under the guidance of a healthcare provider. adjustments in dosages or the timing of administration might be necessary to ensure both drugs achieve their intended effects without causing unwanted interactions.

Additional Blogs for Canadian Nursing - Canadian Nursing dfgdfgdfg

In your journey to get Canadian Psychiatric/Mental Health Nursing Examination certified it is important for you to have all information related to your exam. So we have pulled together a list of additional blogs that may be of interest to you because that are all related to the Canadian Nursing.

Exam Edge Blogs for Canadian Nursing - Canadian Nursing