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CMSN- Canadian Medical-Surgical Nursing (CMSN) Practice Tests & Test Prep by Exam Edge - Related Blogs



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Canadian Medical-Surgical Nursing Examination - Blogs Sample Questions

What is the function of coagulation Factor Protein C?

Correct Answer:
"inactivates va and viiia."


protein c plays a critical role in the regulation of blood coagulation, an essential process that prevents excessive bleeding when blood vessels are injured. specifically, protein c functions to limit the extent of blood clot formation through its action on coagulation factors va and viiia. once activated, protein c, often abbreviated as apc (activated protein c), targets and inactivates these two factors, which are crucial components in the clotting cascade.

factor va and factor viiia are pro-coagulant proteins that significantly amplify the production of thrombin, the enzyme responsible for converting fibrinogen to fibrin, ultimately leading to clot formation. by inactivating factors va and viiia, activated protein c reduces the amount of thrombin produced. this action serves to balance clot formation, ensuring that clots form sufficiently to stop bleeding but not excessively, which could lead to harmful thrombosis.

the activation of protein c itself is facilitated by thrombin, which forms a complex with another protein called thrombomodulin on the surface of endothelial cells (the cells lining the blood vessels). this interaction not only activates protein c but also changes the activity of thrombin from a pro-coagulant to an anticoagulant role.

protein s, another critical component of the coagulation system, serves as a cofactor for activated protein c. it enhances the efficiency with which apc inactivates factors va and viiia. however, the activity of protein s can be moderated by its binding to c4b-binding protein, which renders it inactive and thus influences the effectiveness of the anticoagulant pathway mediated by protein c.

through this finely tuned interplay of activation and inhibition, protein c and its cofactor, protein s, help maintain the delicate balance between clot formation and dissolution, crucial for preventing both excessive bleeding and dangerous clotting. this mechanism underscores the sophisticated nature of the body's regulation of hemostasis (the cessation of bleeding), highlighting the importance of each component in the coagulation cascade.

Additional Blogs for Canadian Nursing - Canadian Nursing dfgdfgdfg

In your journey to get Canadian Medical-Surgical Nursing Examination certified it is important for you to have all information related to your exam. So we have pulled together a list of additional blogs that may be of interest to you because that are all related to the Canadian Nursing.

Exam Edge Blogs for Canadian Nursing - Canadian Nursing